Hydroxy-EG3-undecanethiol
![Hydroxy-EG3-undecanethiol](./img/1560571524_1.gif)
Self Assembled Monolayer Reagent
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Product codeH354 Hydroxy-EG3-undecanethiol
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CAS No.130727-41-2
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Chemical name11-Mercaptoundecanol triethyleneglycol ether
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MWC17H36O4S=336.53
Unit size | -- | |
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10 mg | Please inquire distributors about price. | |
100 mg | Please inquire distributors about price. |
Chemical Formula
Product Description
Polyethyleneglycols (PEGs) are widely used for material modifications to improve hydrophilicity of the surface. PEG-coated materials are usually more stable under physiological conditions. Since Hydroxy-EGn-undecanethiol has 3 or 6 ethylene glycol units, 11 carbon atoms, and an SH group at the end, it can be used to prepare a highly oriented and hydrophilic SAM on a gold surface which is suitable for biomaterial-labelings on the surface. This is due to the improvement of hydrophilicity. The hydrophilic surface can prevent proteins or other biomaterials from non-specific binding. Therefore, the SAM prepared by this reagent will provide a better surface to develop biomaterial sensors or DNA/ protein microarrays. Hydroxy-EGn-undecanethiols (n=3, 6) are used to dilute Carboxyl -SAM or Amino-SAM according to the density of the molecules be introduced onto the surface. There are several papers available on labeling proteins such as ovalbumin, and cytochrome C.
References
C. Pale-Grosdemange, et al., Anal. Chem., 71, 777 (1999);
X. Qian, et al., Anal. Chem., 74, 1805 (2002);
M. Kyo, et al., Anal. Chem., 77, 7115 (2005);
A. Subramanian, et al., Biosensors and Bioelectronics, 21, 998 (2006).
Handling and storage condition
Appearance: | Colorless to pale yellow liquid |
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Purity (HPLC): | ≧ 90.0 % |
NMR spectrum: | Authentic |
-20°C, Nitrogen substitution |