Hydroxy-EG6-undecanethiol
![Hydroxy-EG6-undecanethiol](./img/1560572213_1.gif)
Self Assembled Monolayer Reagent
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Product codeH355 Hydroxy-EG6-undecanethiol
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CAS No.130727-44-5
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Chemical name11-Mercaptoundecanol hexaethyleneglycol ether
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MWC23H48O7S=468.69
Unit size | Price | Item Code |
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10 mg | H355-10 | |
100 mg | H355-12 |
Chemical Formula
Product Description
Polyethyleneglycols (PEGs) are widely used for material modifications to improve hydrophilicity of the surface. PEG-coated materials are usually more stable under physiological conditions. Since Hydroxy-EGn-undecanethiol has 3 or 6 ethylene glycol units, 11 carbon atoms, and an SH group at the end, it can be used to prepare a highly oriented and hydrophilic SAM on a gold surface that is suitable for biomateriallabelings on the surface. This is due to the improvement of hydrophilicity. The hydrophilic surface can prevent proteins or other biomaterials from non-specific binding. Therefore, the SAM prepared by this reagent will provide a better surface to develop biomaterial sensors or DNA/protein microarrays. Hydroxy-EGn-undecanethiols (n=3, 6) are used to dilute Carboxyl -SAM or Amino-SAM according to the density of the molecules be introduced onto the surface. There are several papers available on labeling proteins such as ovalbumin and cytochrome C.
References
1. C. Pale-Grosdemange, E. S. Simon, K. L. Prime, and G. M. Whitesides, Anal. Chem., 1999, 71, 777.
2. A. Subramanian, J. Irudayaraj, and T. Ryan, Biosensors and Bioelectronics, 2006, 21, 998.
3. X. Qian, S. J. Metallo, I. S. Choi, H. Wu, M. N. Liang and G. M. Whitesides, Anal. Chem., 2002, 74, 1805.
4. M. Kyo, K.Usui-Aoki, H. Koga, Anal. Chem, 2005, 77, 7115.
Handling and storage condition
Purity (HPLC): | ≧ 90.0 % |
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Appearance: | Colorless to pale yellow liquid |
NMR spectrum: | Authentic |
-20°C, Nitrogen substitution |