Application: SAM preparation, NTA group coating

Chemical Name: 3,3′-Dithiobis[N-(5-amino-5-carboxypentyl)propionamide-N,N’-diacetic acid] dihydrochloride

Appearance: White or slightly yellow powder
Purity: ≥95.0% (Titration)
MW: 771.68,C26H44Cl2N4O14S2

Storage Condition: ambient temperature, protect from metal
Shipping Condition: ambient temperature


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Structural Formula

Product Description

Dithiobis(C2-NTA) is utilized for the modification of a gold surface to introduce NTA groups that can bind most heavy metal ions. It forms SAMs similar to the other alkanethiols. The SAMs prepared using Dithiobis(C2-NTA) are highly unidirectional due to its alkyl chain interactions. Ni(II)-NTA chelates are commonly used for Histidine-tagged (His-tag) protein purification or separation. Therefore, Ni(II)-NTA-coated gold can be used for His-tag protein analyses. Dithiobis(C2-NTA) is soluble in water and alcohol. It is also referred to as disulfide-NTA in some papers.

When it is difficult to take out all the powder from the container,
please add the solvent into a container and dissolve it before its use.

Piezo electric sensor for endocrine-disrupting chemicals using receptor-co-factor interaction
M. Murata, C. Gouda, K. Yano, S. Kuroki, T. Suzutani, Y. Katayama, Anal. Sci., 2003, 19, 1355.

Gene mutation assay using a MutS protein-modified electrode
Aishan Han, Taiki Shibata, Tohru Takarada, and Mizuo Maeda, Nucleic Acids Symp Ser, 2002, 2: 287,

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Surface Chemistry Cell Staining

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