It has been reported that sulfobetaine derivative- introduced SAM produces low unspecific binding under ion intensity above 200 mmol/l and mildly alkaline conditions. It is, however, possible to prepare biosensor with higher sensitivity by using the unique characteristics of sulfobetaine derivative-introduced SAM with other thiol and disulfide reagent mixure SAM. In addition, Ostuni et al. used Dojindo’s sulfobetaine3-undecanethiol for patterning research of bacteria and mammalian cells on gold substrate. Therefore, sulfobetaine derivatives are applicable in patterning research using biological materials.
When it is difficult to take out all the powder from the container,
please add the solvent into a container and dissolve it before its use.
2) E. Ostuni, R. G. Chapman, M. N. Liang, G. Meluleni, G. Pier, D. E. Ingber, G. M. Whitesides, Langmuir, 2001, 17, 6336-6343