Multichannel evaluation in Cell proliferation or Cell cytotoxicity is important. It’s vital for double-checking them and detailed cell proliferation or cytotoxic effects. Cell proliferation was evaluated by WST-8 assay and Brdu assay; Cell cytotoxicity was checked by LDH assay, WST-8 assay and trypan blue exclusion in this report. see more Using measurements from the LDH assay, WST-8 assay and ATP content in primary cultured hepatocytes, Fujimoto et all. reported that SOD2 Knockout mice were useful as an animal model of liver injury or mitochondrial toxicity. see more